{"id":3230,"date":"2022-08-17T15:24:42","date_gmt":"2022-08-17T15:24:42","guid":{"rendered":"https:\/\/afiyafrica.com\/?p=3230"},"modified":"2022-08-17T15:29:01","modified_gmt":"2022-08-17T15:29:01","slug":"dossier-helicobacter-pylori","status":"publish","type":"post","link":"https:\/\/afiyafrica.com\/index.php\/dossier\/dossier-helicobacter-pylori\/","title":{"rendered":"Dossier : HELICOBACTER PYLORI"},"content":{"rendered":"
\n
\n \t<\/i> Read Time:<\/span>1 Minute, 45 Second <\/div>\n\n <\/div>

C’est une bact\u00e9rie de la famille des Helicobacteriaceae ; BGN.<\/p>\n

Epid\u00e9miologie :<\/strong><\/h4>\n

-colonise l’estomac de la moiti\u00e9 de la population mondiale
\n-pr\u00e9valence plus forte dans les pays en d\u00e9veloppement ( 70%)
\n-impliqu\u00e9 dans les pathologies de la muqueuse gastrique
\n-puissant inducteur de l\u00e9sions pr\u00e9canc\u00e9reuses et de gastrites chroniques
\n-l’infection peut passer inaper\u00e7ue pendant des ann\u00e9es.<\/p>\n

Mode de transmission :<\/strong><\/h4>\n

-oro-orale
\n-f\u00e9co-orale
\n-gastro-orale
\n-transmission iatrog\u00e8ne ( \u00e0 travers mat\u00e9riel d’endoscopie mal d\u00e9sinfect\u00e9)
\n-transmission par les sources d’eau et aliments contamin\u00e9s.<\/p>\n

Facteurs favorisants:<\/strong><\/h4>\n

-\u00e2ge : pr\u00e9valence augmente avec l\u00a0\u00bb\u00e2ge
\n-pauvret\u00e9
\nATCD familiaux de cancer gastrique
\n-r\u00e9gime riche en sel<\/p>\n

Physiopathologie:<\/strong><\/h4>\n

C’est un processus tr\u00e8s long pouvant atteindre 40 ans, associant plusieurs facteurs. Nous avons essay\u00e9 de vous faire un petit r\u00e9sum\u00e9 \ud83d\udc47\ud83c\udfff\ud83d\udc47\ud83c\udfff<\/p>\n

Apr\u00e8s infection, la muqueuse normale sera colonis\u00e9e et quelques semaines ou mois plus tard la gastrite chronique superficielle va s’installer. Sous l’effet de l’augmentation de la prolif\u00e9ration cellulaire et de certains facteurs nutritionnels, la gastrite chronique deviendra atrophique qui plus tard va conduire \u00e0 une m\u00e9taplasie intestinale quelques ann\u00e9es apr\u00e8s. Sous l’effet de certains facteurs, il y aura une dysplasie qui aboutira un cancer superficiel, puis un cancer avanc\u00e9 et apr\u00e8s \u00e0 des m\u00e9tastases.
\nExamens demand\u00e9s<\/p>\n

1-Examens biologiques
\n-recherche d’H.pylori dans les selles
\n-s\u00e9rologie : recherche d’anticorps anti-H.pylori
\n-test respiratoire \u00e0 l’ur\u00e9e marqu\u00e9e.<\/p>\n

2-Autres examens
\nfibroscopie \u0153so-gastro-duod\u00e9nale avec pr\u00e9l\u00e8vement d’une pi\u00e8ce pour examen anatomo-pathologique.<\/p>\n

Quelles sont les complications?<\/strong><\/h4>\n

-cancer gastrique
\n-lymphome de MALT
\nTraitement<\/p>\n

Le traitement dure 7 \u00e0 14 jours et repose sur l’association d’un inhibiteur de pompe \u00e0 proton et de deux ou trois antibiotiques.
\nIPP: om\u00e9prazole (20mg\u00d72), lansoprazole (30mg\u00d72),pantoprazole (40mg\u00d72), esomeprazole(20mg\u00d72),rabeprazole (20mg\u00d72)
\nLes antibiotiques:
\nAmoxicilline ( 1g\u00d72)
\nClarithromycine(500mg\u00d7 2)
\nM\u00e9tronidazole (500mg\u00d72)
\nLevofloxacine ( 500mg\/jour)
\nRifabutine (150-300mg\/jour)
\nTetracycline (500mg\u00d74 par jour)
\nBismuth ( 240-525 mg \u00d7 4 par jour)<\/p>\n

NB<\/strong>: \u00e0 l’issu du traitement, il faut confirmer l’\u00e9radication, le plus souvent par test respiratoire et assurer une surveillance endoscopique et histologique en cas de l\u00e9sion pr\u00e9 n\u00e9oplasique.<\/p>\n

\"\"
\nSource : Helicobacter Pylori : diagnostic, indications et modalit\u00e9s d\u2019\u00e9radication\u00a0Fr\u00e9deric HELUWAERT<\/p>\n

\u00c9crit par Dr G\u00e9raud Estimodo AGBEGBANOU<\/p>\n

\n
\n \n
\n \n \"Happy\"\n <\/a>\n
\n Happy <\/div>\n
\n 0<\/span>\n \n 0<\/span> %<\/span>\n <\/div>\n <\/div>\n\n
\n \n \"Sad\"\n <\/a>\n
\n Sad <\/div>\n
\n 0<\/span>\n 0<\/span> %<\/span>\n <\/div>\n <\/div>\n\n
\n \n \"Excited\"\n <\/a>\n
\n Excited <\/div>\n
\n 0<\/span>\n 0<\/span> %<\/span>\n <\/div>\n <\/div>\n\n
\n \n \"Sleepy\"\n <\/a>\n
\n Sleepy <\/div>\n
\n 0<\/span>\n \n 0<\/span> %<\/span>\n <\/div>\n <\/div>\n\n
\n \n \"Angry\"\n <\/a>\n
Angry<\/div>\n
\n 0<\/span>\n 0<\/span> %<\/span>\n \n <\/div>\n <\/div>\n\n
\n \n \"Surprise\"\n <\/a>\n
Surprise<\/div>\n
\n 0<\/span>\n 0<\/span> %<\/span>\n <\/div>\n <\/div>\n\n <\/div>\n <\/div>\n\n ","protected":false},"excerpt":{"rendered":"

C’est une bact\u00e9rie de la famille des Helicobacteriaceae ; BGN. Epid\u00e9miologie : -colonise l’estomac de…<\/p>\n","protected":false},"author":1,"featured_media":3233,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[13,150],"tags":[782],"class_list":["post-3230","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dossier","category-maladies","tag-helicobacter-pylori"],"yoast_head":"\nDossier : HELICOBACTER PYLORI -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/afiyafrica.com\/index.php\/dossier\/dossier-helicobacter-pylori\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dossier : HELICOBACTER PYLORI -\" \/>\n<meta property=\"og:description\" content=\"C’est une bact\u00e9rie de la famille des Helicobacteriaceae ; BGN. 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